- Prior to March 8th, 2016 update, the crafting recipe for the Booster Shot required Healing Salves and 4 Papyrus, instead of 8 Rots and 2 Nitres.
- The booster shot is used for medicine to upgrade the body's immune system to fight a virus that may come later in life if not given the booster shot. However, in Don't Starve Together, the booster shot is used after the character has been affected by maximum health penalties.
- Having Rot as an ingredient refers to Penicillin, an anti-biotic derived from mold.
- Booster ShortはShadow Creatureに対して使用することができますが何の効果もありません。